Friday, January 20, 2017

Getting pregnant later in life has its risks

Getting pregnant later in life has its risks

If you’re older than 35 and hoping to get pregnant, you’re in good company. Many women are delaying pregnancy well into their 30s and beyond – and delivering healthy babies. Taking special care can help give your baby the best start.
The biological clock is a fact of life, but there’s nothing magical about age 35. It’s simply an age at which various risks become more discussion-worthy.
For example:
• It might take longer to get pregnant. You’re born with a limited number of eggs. As you reach your mid- to late 30s, your eggs decrease in quantity and quality.
An older woman’s eggs also aren’t fertilised as easily as a younger woman’s eggs. If you’re older than 35 and haven’t been able to conceive for six months, consider asking your health care provider for advice.
• You’re more likely to have a multiple pregnancy. The chance of having twins increases with age. The use of assisted reproductive technologies – such as in vitro fertilisation – also can play a role.
• You’re more likely to develop gestational diabetes. This type of diabetes, which occurs only during pregnancy, is more common as women get older.
Tight control of blood sugar through diet and physical activity is essential. Sometimes medication is needed, too.
Left untreated, gestational diabetes can cause a baby to grow significantly larger than average – which increases the risk of injuries during delivery.
• You’re more likely to develop high blood pressure during pregnancy. Research suggests that high blood pressure that develops during pregnancy is more common in older women.
Your health care provider will carefully monitor your blood pressure and your baby’s growth and development. You might need to take medication or deliver your baby before your due date to avoid complications.
• You’re more likely to have a low birth weight baby and a premature birth. Premature babies, especially those born earliest, often have complicated medical problems.
• You might need a C-section. Older mothers have a higher risk of pregnancy-related complications that might lead to a C-section delivery, such as placenta previa – a condition in which the placenta blocks the cervix.
• The risk of chromosome abnormalities is higher. Babies born to older mothers have a higher risk of certain chromosome problems, such as Down syndrome.
• The risk of pregnancy loss is higher. The risk of pregnancy loss – by miscarriage and stillbirth – increases as you get older, perhaps due to pre-existing medical conditions or foetal chromosomal abnormalities.
Ask your health care provider about monitoring your baby’s well-being during the last weeks of pregnancy.
While further research is needed, studies suggest that a man’s age at the time of conception – his paternal age – also might pose health risks for his children. – Mayo Clinic News Network/Tribune News Service

Saturday, January 14, 2017


BY: Byron J. Richards, Board Certified Clinical Nutritionist
Image result for brain damage

Neurontin and its newer more potent version, Lyrica, are widely used for off-label indications that are an outright flagrant danger to the public. These blockbuster drugs were approved for use even though the FDA had no idea what they actually did in the brain. A shocking new study shows that they block the formation of new brain synapses1, drastically reducing the potential for rejuvenating brain plasticity – meaning that these drugs will cause brain decline faster than any substance known to mankind.
The problem of these drugs is compounded by their flagrant illegal marketing. Neurontin was approved by the FDA for epilepsy back in 1994. The drug underwent massive illegal off-label promotion that cost Warner-Lambert 430 million dollars (the very first big fine for off-label promotion). The drug is now owned by Pfizer. Pfizer also owns Lyrica, a super-potent version of Neurontin. It has been approved by the FDA for various types of pain and fibromyalgia. Lyrica is one of four drugs which a subsidiary of Pfizer illegally marketed, resulting in a $2.3 billion settlement against Pfizer.
Even though the marketing of these drugs has been heavily fined, they continue to rack up billions in sales from the off-label uses. Doctors use them for all manner of nerve issues because they are good at suppressing symptoms. However, such uses can no longer be justified because the actual mechanism of the drugs is finally understood and they are creating a significant long-term reduction in nerve health.
The researchers in the above study try to downplay the serious nature of the drugs by saying “adult neurons don’t form many new synapses.” That is simply not true. The new science is showing that brain health during aging relies on the formation of new synapses. Even these researchers managed to question the common use of these medications in pregnant women. How is a fetus supposed to make new nerve cells when the mother is taking a drug that blocks them?
These are the kind of situations the FDA should be all over. As usual, the FDA is sitting around pondering a suicide warning for Lyrica while its off-label uses include bi-polar disorder and migraine headaches. The FDA is likely to twiddle its thumbs for the next decade on the brain damage issue. Consumer beware.


Wednesday, January 11, 2017

Here’s why you may want to avoid eating this during Chinese New Year

Here’s why you may want to avoid eating this during Chinese New Year
Eating large amounts of cured meats was linked to worse symptoms among asthma sufferers, a French study found.
That was true even after taking obesity into account, the authors say.
So-called cured meats have been preserved and flavoured by the addition of various combinations of salt, nitrates, nitrites, and sugar. Examples of such processed meats include bacon, ham, prosciutto, corned beef, pastrami, and pepperoni. Waxed duck, cured pork belly and Chinese sausages are also examples of cured meats that are favoured during Chinese New Year.
“Cured meat intake, a typical food in industrialised societies, has been associated with many chronic diseases, including lung cancer and Chronic Obstructive Pulmonary Disease (COPD), but its association with asthma remained unclear,” study leader Dr Zhen Li said. Li is a researcher at Inserm and Paul Brousse Hospital in Villejuif.
As reported in Thorax, the research team had data on 971 adults from five French cities who answered questions about diet, weight, and asthma symptoms between 2003 and 2007.
On average, participants ate 2.5 servings of cured meats per week.
Just over 40% of the participants said they had had asthma at some point, and around half said they had never smoked. Each participant was assigned an asthma symptom score, ranging from zero to five, based on difficulty breathing, chest tightness, and shortness of breath during the previous year.

Those who frequently ate cured meats were found to be 76% more likely to see a worsening of asthma symptoms.
Those who frequently ate cured meats were found to be 76% more likely to see a worsening of asthma symptoms.
Follow-up surveys completed between 2011 and 2013 showed that about half of the participants had no changes in their asthma scores, over one-fourth said their symptoms had improved and about 20% felt their symptoms had gotten worse.
After accounting for other factors such as smoking, physical activity, age, other dietary habits, and education, researchers found that participants who ate the most cured meat (four or more servings per week) were 76% more likely to see a worsening of symptoms compared to those who ate the least (less than one full serving per week).
About 35%  of the participants were overweight and about 10% were obese, based on their responses. Those conditions probably explained about 14% of the association, the authors estimated.
“Our finding, together with other previous findings, suggests that patients with asthma might have benefits by following a multiple-interventional program,” Li said. “That means, besides the medication, weight control as well as dietary intervention such as reducing cured meat intake might also help them to control their asthma symptoms.”
Dr Sunit Jariwala complimented the study but noted that its observational design means it can’t prove cause-and-effect.
“Cured meats are rich in nitrites which may lead to any kind of oxidative stress related lung damage and asthma,” said Jariwala, who is director of allergy and immunology research at the Albert Einstein College of Medicine and Montefiore Medical Center in New York City.
Jariwala, who was not involved in the study, believes obesity is an important consideration with asthma patients.
“In this study, as well as previous studies, obesity may be linked to systemic inflammation that can worsen asthma as well as other obesity related conditions such a sleep apnea,” he said.
Jariwala advises patients to follow a balanced diet that includes fresh, unprocessed foods and is low in salt, sugar, and saturated fats. – Reuters

Tuesday, January 10, 2017

Glujoint 25g x 20 sachets @RM120 in Johor Bahru

Image result for Glujoint 25g x 20 sachets

Product details of Glujoint 25g x 20 sachets

New Generation Approach for Joint Health.
Mixed Organic Soy Milk with Collagen Hydrolysate (CH)

Supplement Facts:
  • A blend of a proprietary ingredients, Collagen Hydrolysate, Tricalcium Phosphate and Soy Milk.
  • Available in 25g x 20 sachets
  • Patented ingredient from Germany

The ingredients in GluJoint may help in:
  • Promoting mobility of joint, tendon and ligament.
  • Relieving discomfort from overused joints and joint injuries.
  • It contains basic amino acids essential for the joints and for those who has low protein level due to poor diet.
  • It also contains collagen which helps in lubricating the joint and improve joint health.

  • Use this product as a food supplement only.
  • If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your doctor before use.
  • Discontinue use and consult your doctor if any adverse reactions occur.
  • Keep out of reach of children.
  • Do not use if sachet is torn.

  • Store in a cool, dry place.

  • One (1) sachet daily.
  • Serve in a glass of room temperature water. Drink immediately.
  • For those with gastric problem or sensitive stomach, preferably take after a meal.

Tuesday, January 3, 2017

If you really want to have super memory in 2017, start doing this !!!

If you really want to have super memory in 2017, start doing this
A new study adds to the growing evidence that exercise can help to improve memory. Photo: AFP/Istock

Presented at the annual conference of the British Psychological Society’s Division of Sport and Exercise Psychology in Cardiff by Dr David Marchant from Edge Hill University, Lancashire, England, the research looked at the effect of cycling on memory in two different experiments.
Ten healthy and physically active participants were given lists of words to learn and recall either after or before 30 minutes of moderate intensity cycling, or before or after a period of rest which involved quiet, seated reading.
The results showed that participants’ performance in recalling words immediately after learning them improved if they had exercised before learning rather than resting, suggesting that an acute bout of aerobic exercise improves short-term memory.
When participants were asked to wait 30 minutes between learning and recall, exercising before or after learning also produced a better performance than resting.
However the best recall was seen in those participants who exercised after learning the words.
The findings are also in line with previous research which also suggests that physical activity improves memory and could be beneficial for those who need to learn new information.

Working out can really help those who need to learn and remember new information.
Working out can really help those who need good memory to retain new information.
A study released back in June which looked at running also suggested that exercise could help improve memory, by boosting levels of a certain protein in the blood. Carried out by a team of US and German researchers the animal study found that cathepsin B, a protein that can be secreted by muscle tissue during exercise and transported to the brain, had a positive effect on the recall ability of the mice who had run before undergoing a daily recall test compared to those who didn’t run and didn’t produce the protein.
Meanwhile a small-scale, qualitative study by Michigan State University researchers also found a link between memory and fitness. After following 75 college students over a two-day period, the team saw that those with the lowest fitness levels struggled the most to retain information, with the study’s authors suggesting that those with a low level of fitness lose more memory across time.
And when looking at the effect of exercise on memory in older adults a small-scale study from the University of Boston found that older adults who take more steps by either walking or jogging perform better on memory tasks than those who are less active.
Two studies from March this year which looked into the effect of exercise on Alzheimer’s also found that physical activity had a positive effect on memory. Not only did those who exercise benefit from a reduced risk of the condition, but in one study those who took part in physical exercise also showed larger gray matter volumes in the key areas of the brain that are associated with memory. – AFP Relaxnews

Sunday, December 25, 2016

Common heartburn drugs may raise stroke risk

                                     Image result for proton pump inhibitors
Proton pump inhibitors are a class of drugs commonly used to treat heartburn - pain in the chest or throat caused by the rising of stomach acid into the esophagus. But new research suggests this medication should be used with caution, after finding it could raise the risk of ischemic stroke.

Image result for women with reflux disease
A new study has linked the use of PPIs - drugs that treat heartburn - to greater risk of ischemic stroke.
In a study of almost 245,000 Danish adults, researchers found the risk of ischemic stroke was increased by a fifth with the use of proton pump inhibitors (PPIs).
PPIs work by reducing the amount of acid produced in the stomach, thereby reducing the "backing up" of stomach acid into the esophagus - a condition known as heartburn. Someone who has heartburn more than twice a week may have gastroesophageal reflux disease (GERD).
Lead study author Dr. Thomas Sehested, of the Danish Heart Foundation in Copenhagen, Denmark, recently presented his findings at the American Heart Association's Scientific Sessions 2016, held in New Orleans, LA.
Ischemic stroke occurs when the artery that supplies the brain with oxygen-rich blood becomes blocked, usually by a blood clot. Ischemic stroke is the most common form of stroke, accounting for around 85 percent of all strokes.
Dr. Sehested and colleagues note that previous studies have associated PPI use with vascular impairment, which led the scientists to investigate whether the drugs might raise the risk of ischemic stroke, "especially given their increasing use in the general population," notes Dr. Sehested.

Ischemic stroke risk 21 percent higher with PPI use

To reach their findings, the team analyzed data of 244,679 adults from Denmark - of an average age of 57 years - who underwent endoscopy to pinpoint the causes of their stomach pain or indigestion.
During an average of 6 years of follow-up, 9,489 patients experienced a first-time ischemic stroke.
The researchers assessed patients' use of one of four PPIs - omeprazole (Prilosec), pantoprazole (Protonix), lansoprazole (Prevacid), and esomeprazole (Nexium) - and looked at whether this was associated with ischemic stroke risk.
Overall, the team found that patients were at 21 percent greater risk of ischemic stroke when they were using PPIs, compared with when they were not using the drugs.
There was little or no greater risk of stroke with low doses of PPIs, the researchers report, and another group of medications used to treat heartburn - called H2 blockers - were not linked to increased stroke risk.
Looking at stroke risk among the highest doses of each of the four PPIs, the researchers found pantoprazole fared worst, increasing the risk of ischemic stroke by 94 percent.

Study 'questions the cardiovascular safety of PPIs'

The researchers accounted for a number of possible confounding factors, including age, gender, high blood pressureatrial fibrillation, and use of medications that have been linked to poorer cardiovascular health.
Because the study is purely observational, the researchers are unable to prove cause and effect between PPI use and increased stroke risk. Still, they believe the results suggest patients should be cautious about using the drugs, many of which are now available over the counter.
Dr. Sehested notes that doctors should also apply caution when deciding whether to prescribe PPIs to patients and for how long. "We know that from prior studies that a lot of individuals are using PPIs for a much longer time than indicated, which is especially true for elderly patients," he adds.
The team concludes that a randomized, controlled trial of the association between PPI use and the risk of cardiovascular disease is needed.

6 Ways to Save Money on Your Prescription Medications

Image result for save medicine cost in singapore
If you are taking a medication for a chronic condition (hypertension, high cholesterol, diabetes, etc.), there’s a chance that you might be paying more than you actually need to pay. You might be able to get the same type of drug to treat the same condition for a mere fraction of the cost. And I’m not just talking about choosing generic over brand name. There’s something that’s even better than that, something that most Singaporeans are not aware of.
1. Choosing Generic Medications
Yes, you definitely can save tons of money choosing a generic over a brand name drug. Generics have active ingredients that are chemically identical and biologically identical (this means they are made to function the same way) to their brand name counterpart. They are also manufactured and regulated under the same standards. Brand name medications are all recently patented (their “monopoly” hence gives them the ability to charge such a high price), which may imply that there is something extraordinary about their composition or formula, but many reports and studies have shown that the majority of recent brand name medications are just “me-too drugs”. These are drugs that are nearly identical to already existing drugs, but with minor changes that allow it to be classified as “novel” and hence be patentable. 
For example, when AstraZeneca’s patent for their top selling medicine Prilosec (generic name: Omeprazole) was ending, it found a way to further purify the active ingredient (changing it very slightly and insignificantly) to Esomeprazole. They gave it a new name (Nexium) and a new patent. The efficacy of the two medications are nearly identical but the new one costs a LOT more. For most conditions, generic medications are not only cheaper, they are just as good as the brand name.
2.Choosing Formulary Medications
For many medical conditions, there are a variety of prescription drugs that belong to the same class. These essentially do the same thing, but are chemically different (unlike brand and generic which are chemically identical). The formulary is a list of medications which are published on the MOH website that are subsidized for Singaporeans and PRs. Those which are on Standard Drug List #1 are capped at $1.40 per week and $2.10 per week for Singaporeans and PRs, respectively. Those which are on Standard Drug List #2 are subsidized by 50% and by 25% of the retail price for Singaporeans and PRs, respectively. Keep in mind that each polyclinic and specialist outpatient clinic may stock different medications and implement this differently, but this formulary will at least give you a starting point. If you have a chronic medical condition, more than likely there is a medication on the formulary that you can switch to that is highly subsidized. According to MOH, the formulary covers about 90% of the total volume of medication prescriptions. For example, if you have hypertension, and you choose a generic drug, you will still have a big price difference between generic drugs of the same class. Losartan 100mg is $0.40 per pill and Candesartan 16mg is $1.10 per pill. But Losartan is on the formulary Stardard Drug List #2 while Candesartan is not. So that means if you’re Singaporean, Losartan is only $0.20 per pill. Despite both medications being generic medications, one will cost more than $400 per year and the other will only be $73. Choosing generic medications does save you money, but choosing formulary medications can save you even more!
3.Splitting your pills
Many pills cost the same despite how much active ingredient there is in the pill. For example, Amlodipine 5mg is $0.20 and Amlodipine 10mg is also $0.20. If you need only 5mg, why not just buy the 10mg and split the pill in half? Many tablets can be split in half, but do not try to split capsules or any time-released or coated medications. If the pill is not scored, always check with your doctor or pharmacist to make sure it is safe to split the pill.
4.Choosing Not to Combine Medications
Combination medications are great for convenience, but many of these tend to be brand name medications, such as Caduet, in which Pfizer just put two already available generic drugs together (Amlodipine plus Atorvastatin) to patent a “new” drug. You may want to ask your doctor whether you can take the medications separately, which may allow you to save money, especially since both generic drugs (as in this example) are on the MOH formulary list.
Image result for save medicine cost in singapore
5.Shopping Around
As with everything, you should shop around and call your pharmacy since prices will vary. You may be wondering why prices vary in the first place. Like other commodities, the institution or business which purchases the goods have different price arrangements with the suppliers. Larger institutions, in general, have more buying power. There may be other special discounts or costs that affect the price of the medication.

6. Visit Pharmacy in Malaysia, Johor Bahru
Usually, medicine in malaysia is selling at lower price compare to Singapore. Can refer below link for reference.

Why doesn’t my doctor just give me the less expensive drug?
Many people think that doctors purposely prescribe the most expensive drug because they get financial incentives. For the vast majority of doctors, this is not the case. Yes, there are some that get kickbacks, but those working in the public institutions are strictly prohibited from this (this is one reason I avoid private hospitals and clinics). The prescribing habits of doctors are just that – habits. They prescribe what they are comfortable with and what they have prescribed in the past. They also place a higher priority on what works for their patients, and have less interest in knowing what cheaper alternatives are out there. It’s like when I ask people which place has the best laksa, they each have their own preference and some places will be a lot more expensive than others. No one ever tells me the cheapest place, unless they extensively research this. There also may be a good reason why your doctor wants you on a more expensive drug. The key is to ask your doctor and engage him/her in a conversation to discuss possible less expensive alternatives. The prices of drugs prescribed for common conditions can be found on the Pharmaceutical Society of Singapore website.
Of course, the best way to save money on medications is to live a healthy lifestyle so you won’t need to be on the medications. Most chronic conditions can be managed or even reversed with lifestyle modifications. How we eat, move, sleep, think, and interact with others can significantly change our health, our savings, and our life.