Viartril S 1500mg (Glusosamine Sulphate) 30 sachet @ RM125 in Johor Bahru

Viartril®-S is the Crystalline Glucosamine Sulfate. It is the original and only Glucosamine Sulfate that has been fully tested in clinical trials for safety and efficacy.Clinical studies and the world-wide clinical experience have shown that Viartril®-S relieves the symptoms (pain and function limitation) of osteoarthritis (1). Recent, state-of-the-art clinical trials have also demonstrated that Viartril®-S is the first compound that, when given for long-term treatment courses (i.e. at least 3 years), can decrease the progression of osteoarthritis (2,3).

How does Viartril®-S work?

Anabolic-Effect – Viartril®-S stimulates the synthesis of proteoglycans, the building blocks of the Cartilage Matrix 

(4,5,6) .

Anti-Inflammatory & Anti-Catabolic – Viartril®-S depress cartilage degradation activities by inhibiting the action of catabolic enzymes (6,7,8,9,10,11,12,13,14,15).

What is Glucosamine Sulfate?

Glucosamine Sulfate is the salt of the natural amino-sugar glucosamine, which is normally synthesized in the healthy body and is the preferred substances that form the cartilage matrix that are essential for cartilage health and function.

Is the original Glucosamine Sulfate contained in Viartril®-S different from other glucosamine products? 

Glucosamine Sulfate, for chemical reasons is a highly unstable compound and cannot exist unless in stabilised form. Products claiming to contain glucosamine sulfate without declaring how it is stabilised, most likely do not contain sufficient of this compound.  

Rotta Research Group has invented and patented several years ago a method to stabilize glucosamine sulfate, through a chemical process of co-precipitation with sodium chloride, thus obtaining Crystalline Glucosamine Sulfate(16).

How much glucosamine should one take daily?

According to the GUIDE studies published, Glucosamine Sulfate at the Oral once-daily dose of 1500mg is the preferred symptomatic medication in knee OA (20) .

1 x Sachet (1500mg)/day

3 x Capsules (500mg)/day

This statement is further supported by an IC50 trial, where 1500mg of Viartril®-S is able to provide maximum Glucosamine Concentration of 8.9μM in the body. This is significantly higher than the minimal requirement of 6.2μM to be effective in treating OA (21).

Viartril®-S contains sodium: Is it contraindicated in hypertension?

The sodium chloride (NaCl) in Viartril®-S is to stabilize the Glucosamine Sulfate through crystallization.NaCl content is 0.128g in each 500mg capsule. Therefore, the recommended daily dosage of capsules contain 0.384g NaCl (similar to 1 sachet).This is small compared with our standard daily intake of 6-10g of NaCl. For a hypertensive patient, a mild dietary sodium restriction of up to 5g NaCl is recommended. Therefore, the small quantity of sodium in Viartril®-S will not affect it. No health authority has ever contraindicated Viartril®-S in hypertension.

Is Viartril®-S safe for shell-fish allergy patients?

Viartril®-S is obtained by a synthesis process (ensuring a high degree of purity), starting from a substance called chitin which is of sea origin.Chitin is a highly purified polysaccharide and it does not contain protein impurities responsible for allergic reactions in certain individuals. Any other potential impurity would be eliminated by the synthesis process. Viartril®-S is therefore not contraindicated for individuals allergic to shell-fish.

Are there any interactions with other drugs when using Viartril®-S?

Due to its physic-chemical and pharmacokinetic properties, Glucosamine Sulfate is a compound with no potential for pharmacokinetic or other interactions with any other drugs.